Part 2: Health apps, wearables, and sensors: The advancing frontier of digital health

When it was set up in 2002, Teach First’s aim was to encourage more graduates to try teach-ing. Amid worries that the best brains in the country were being lured into the City of London, accountancy and law, the idea was to tap some of their brain power for state schools, in an attempt to tackle educational inequality.
12. Is there something I am clinging to? We don’t always realize when we’re clinging to something harmful when it feels safe and familiar, whether it is an unfulfilling job, an unhealthy relationship, or a stagnant way of life. Recognize if you are clinging to something that isn’t serving you and work on taking small steps towards change and release.
达奇斯说:年底iphone5和迷你ipad的发布,消除了海内外制造业和乔布斯死后遗留影响的争议,这使得苹果成为年度最大的赢家。
还记得《类人猿行动》吗.这是一部被众人忽略的2016年早些时候的电影,由杰米.多南和斯里安.墨菲担任主演,讲述了对希特勒身边的三把手、党卫队将军莱因哈德.海德里希进行的一次失败暗杀。《行动代号:猿人》也尝试讲述这一故事,杰克.莱诺和奥康奈尔将在片中饰演密谋的士兵,而罗莎曼德.派克和米娅.华希科沃斯卡是他们片中的感情对象,杰森.克拉科则饰演他们的刺杀目标。
adj. 有才能的,有天赋的
勇士卫冕几乎板上钉钉
Company: Everyone Counts
China's pension insurance balance of urban employees and urban and rural residents added up to four trillion, according to the Annual Report on Social Security Development 2015.
卡塔尔大学被选为最国际化的学校,这也标志着来自中东的大学第一次高居榜首。
"The autonomous region has invested 4 billion yuan (around 600 million US dollars) to promote industries with local features in poor areas, and relocated 77,000 poor people last year," said Lu Huadong, deputy director with the office.
或许,在纽约尼克斯夺取NBA总冠军的道路上,缺失的关键就是甜瓜(安东尼的昵称)。噢,不,等等,林书豪才是他们欠缺的一环。然而,无论怎样,甜瓜不会妨碍尼克斯的冠军梦。
[l?un]
中国上海市场研究公司艾瑞咨询集团(iResearch)此前的一份报告说,中国网络游戏市场2008年收入为人民币208亿元,约占全球市场的27%,这一比例高于韩国的21%,略低于美国的29%。该公司还预计,中国可能会在2009年底前超越美国,成为全球最大的网络游戏市场。
The consequences are more parochial than those of Chinese data distortion. British law requires the ONS to produce the RPI and, given that it refuses to improve the measure, its fiddling affects hundreds of billions of pounds of contracts which continue to be linked to the RPI.
One side of the capsized Eastern Star was rolled above water at 7:30 am Friday, as rescuers worked through the night to right the upturned ship in the Yangtze River. The side that has emerged shows "Eastern Star" in Chinese character on the hull.
感恩节当天,沃尔玛、塔吉特(Target)和Kmart等美国大型零售商都开门营业,以便借假日购物旺季大赚一笔。今年,沃尔玛开始营业的时间甚至比去年早了两个小时。但好市多拒绝加入“黑色星期五狂欢”,感恩节并没有开门营业。首席执行官克雷格杰利内克认为,给员工放一天假比提高公司利润更加重要。
爱你的老公!
The accountancy firm in charge of the Oscars results has apologized after Warren Beatty and Faye Dunaway were handed the wrong results card when announcing the Best Picture award and incorrectly announced La La Land as the winner rather than Moonlight.
但是,房地产经纪公司世邦魏理仕(CBRE)香港机构投资团队主管约翰?戴维斯(John Davies)说,价格下降应会让香港房地产市场变得更加可靠。“这个市场正在显示出机构投资者更了解的成熟市场的特征,”他说。
approval
*Guest Actor in a Drama Series: Hank Azaria, “Ray Donovan”
其实我一直都在等你提到篮网队的处境,既然你没说,那就我来说吧。林书豪已经因腿筋受伤缺阵几周了。他们是唯一有摆烂权利但是不摆烂的球队!
30岁的阿什莉·格林汉姆是首位跻身收入榜单的大码模特,她通过自己的内衣和泳衣品牌代言合同赚得550万美元,排在榜单的第十位。
如果你没听过这句话,你去年绝对没上过中文网。这句简单的话是留在魔兽BBS上的,不知道什么原因——有说法是有网络公司是幕后推手——这句话吸引了710万人点击,在发布后24小时内产生了30万条评论。
去年世锦赛打破男子1500米自由泳世界纪录,孙杨就被认为是中国男子游泳在伦敦实现历史性突破的希望所在。即将开始的伦敦奥运会,孙杨将参加200米、400米和1500米自由泳三项.去年世锦赛孙杨在400米自由泳中不敌朴泰桓屈居亚军,因此他发誓要在伦敦复仇。相比而言,孙杨在1500米的夺金把握更大...


So far this year, companies have announced 376 share-repurchase initiatives for a total of $261 billion, according to data from Birinyi Associates. That's nearly 72% higher than 2012, though slightly lower when compared to the same period in 2013, which was a record year for buybacks.
拉杜卡(Rocco LaDuca)是纽约州尤蒂卡市(Utica)《观察家快报》(Observer-Dispatch)报道犯罪和法院新闻的记者。他说,之所以选择做记者,一定程度上是源于他和祖母读报的美好记忆。
当科比的身体长到了6尺6寸时,高中时期的他已经是一个相当中型身板的家伙。可以想象,在1996年,想抵挡住17岁的科比进攻就很难。我相信,这几乎是不可能的。


With the increasing proliferation and sophistication of mobile phones, wearable devices such as smart watches, and sensors that can measure and gather a variety of data, public interest is growing in using consumer electronics to take ownership of personal health and wellness. A 2015 survey found that 66% of Americans age 66 and older want to use mobile technologies to improve their health by receiving medication reminders and tracking diet and nutrition, physical activity, and symptoms.[1

n. 贡献,捐款(赠)
STEP 8: PRACTICE the method of loci or roman room, or at least pretend to
Losing my future is not like losing an election or a few points on the stock market. I am here to speak for all generations to come. 失去未来不像落选选举或者股市浮动那么简单,我来到这里是为了将来所有的世代而演讲。
A jailed con artist who falls in love with another inmate and escapes prison multiple times could only be the work of fiction, but this is more or less the real story of Steven Jay Russel. Much like his film counterpart, played by Jim Carrey, Russell was originally sent to prison for fraud. He escaped his first sentence to be with his partner Jim Kemple, who at the time was dying from AIDS. Russell was found two years later and returned to prison. Kemple died soon after.

Health apps and wearables
Health apps and wearables can unobtrusively gauge physiological and emotional states and collect, quantify, and monitor data regarding a user’s day-to-day behaviors. This “quantified self” can increase users’ self-awareness regarding their behavior and encourage positive changes to their overall health and well-being.[2] These commercially available devices also integrate an array of features to provide motivation through reward systems, opportunities for social in-teraction, tools for self-improvement, and prompts. The novelty, affordability, practicality, and ease of use have resulted in increased consumer enthusiasm and the pervasiveness of these devices.[3,4] With this growing interest in personal health, members of the general public are becoming more involved in monitoring and improving their own health habits.[5-10

Undoubtedly, merely tracking data through a device is not enough to maintain good health-related behaviors long-term, and the software must also incorporate motivational constructs important for the adoption and habituation of behaviors. For instance, a systematic review of studies that considered the use of electronic activity monitor systems found short-term changes in physical activity with self-monitoring, but no demonstration of superiority when the systems were compared with other interventions.[11] Another review of studies on the viability of using mobile technology for measuring and influencing physical activity found that most apps allow users to document their activity, set goals, review real-time feedback, connect to a social support network, and access online expertise.[12] However, less common among these apps were prompts to act and opportunities for problem solving and action planning, which are crucial constructs that translate intention into long-term behavior change.[13]

Sensor technologies
Sensor technologies have begun to enter the telehealth landscape and are primarily focused on continuous monitoring and precise diagnostics to inform management of various health conditions and diseases.[14-17] Sensors can be integrated into a watch or arm band or adhesive bandages and clothing, and then programmed to collect data on cardiac rhythm, heart rate, blood pressure, respiration, oxygen saturation, galvanic skin response, glucose levels, body temperature, body motions, ambient temperature, and global positioning. For health care providers, sensor inputs can permit remote monitoring, real-time teleconferencing, and timely care for patients with chronic diseases. For both patients and clinicians, telehealth supported by sensors can have profound implications. Clinicians can provide timely and patient-centred care to those living at a distance with chronic disease and can coordinate care when multiple providers are involved, reducing costs to the health care system.

A current clinical example is the management of paroxysmal atrial fibrillation with a mobile ECG and app that monitors the patient’s electrical rhythm to detect frequency and patterns of arrhythmias, and may even allow patients to share ultrasound and electrocardiogram data with their health care provider.[18-20] Telemonitoring with sensors can also support self-management of chronic diseases and detect early signs of deterioration in health requiring immediate treatment and advice.[21] Studies to date have demonstrated some clinical promise for the use of home telemonitoring in the context of heart failure and diabetes. A recent Cochrane review found that telemonitoring was an effective way to lower levels of glycated hemoglobin and low-density lipoprotein.[22] Although several studies on heart failure have produced conflicting results regarding the overall benefits of home monitoring,[23-26] systematic reviews have suggested that home telemonitoring reduces all-cause mortality and hospitalizations, and improves quality of life compared with usual care.[22,27] In addition, features such as automated and mobile telemonitoring appear to be more effective compared with other forms of home telemonitoring.[27]

Further studies are needed to determine how home health monitoring can improve patient safety during the transition from acute care to community care, and to examine the impact of home monitoring on health care costs. TEC4Home (Telehealth for Emergency-Community Continuity of Care Connectivity via Home Tele-monitoring), an initiative of the University of British Columbia and Vancouver Coastal Health, is seeking to do this with prospective trials designed to uncover how telemonitoring can support the safety of heart failure patients discharged from hospital to home.[28]

Mobile apps, wearables, and sensors in the clinical setting
Even though mobile apps, wearables, and sensor technologies are promising, further research is needed to validate their use and long-term impact.[29] This research will require the collaboration of clinicians, health researchers, engineers, and computer scientists.[30] Understanding the possible risks of using these technologies, from physiological harm to breaching of privacy and confidentiality with insecure devices, and how to mitigate any risks is also important. Other important issues to consider include patient anxiety with overuse of technologies, health data piracy, self-diagnosis resulting from overreliance on self-monitoring, and patients not seeking help appropriately. These technologies should be used only as complementary tools in the treatment and prevention of health conditions and disease and should not be used in isolation by patients who self-diagnose and self-manage without consulting a health professional. 

As of mid-July, there were about 50,000 stores running on Bigcommerce, which have collectively sold close to $4 billon using the platform. The developer has typically added new customers one-by-one. However, a deal it struck in early July with eBay positions its service as the preferred migration path for two Magento products that will be discontinued in February 2015, Go and ProStores. Bigcommerce previously migrated more than 5,000 merchants off ProStores, and the deal could potentially bring up to 10,000 more.

Instant Heart Rate by Azumio.[31] A free app downloadable to both Apple and Android operating systems that measures heart rate and displays a monitoring strip. As well as helping users accurately track their heart rates, the app is capable of detecting irregular rhythms when palpitations occur. 

Sleep Time by Azumio.[32] A free app that monitors sleep patterns, sleep efficiency, and also acts as an alarm clock. Users can know how often they go into light and deep sleep, and recognize how much of these types of sleep will be necessary for them to feel rested, thereby quantifying the amount of true sleep they need and not just how long they should stay in bed. 

Bellybio Interactive Breating by RelaxLine.[33] A free app that helps users pace their breathing to achieve calmness. Placing the mobile phone against the abdomen, users can follow the sounds emitted to practise deep, abdominal breathing using this simple yet surprisingly effective tool. 

每个伟大的侦探都需要专属于自己的经典故事。对于福尔摩斯而言,这个故事是《巴斯克维尔的猎犬》。对于阿加莎?克里斯蒂笔下龟毛的比利时侦探赫克尔?波洛而言,这个故事是《东方快车谋杀案》——故事讲述了一个嗜血的恶棍在驶向巴尔干半岛的列车上杀死了一个有钱的商人。真相果真是如此吗?西德尼?吕美特曾在1974年将该故事拍成了一部备受喜爱的电影,强大的演员阵容包括肖恩?康纳利、英格丽?褒曼和阿尔伯特?芬尼(饰演侦探波洛)。如今肯尼思?布拉纳自己戴上了侦探波洛的大胡子,披挂上阵,同时又担当幕后导演。这部新版电影的演员有约翰尼?德普、黛西?雷德利、米歇尔?菲佛、佩内洛佩?克鲁斯和朱迪?丹奇。这个故事还能挖掘出什么新内容呢?也许会有。不过,即使没有,阿婆的粉丝也肯定会去看。这部电影将于11月3日在英国上映,11月10日在美国、中国和土耳其上映,11月30日在中国香港和新加坡上映。(资料来源:二十世纪福克斯电影公司)
格温o史蒂芬尼的广告在好几个应用上同时推出,其中就有总部位于硅谷的短信应用Tango。Tango主要通过用户收件箱里的广告赚钱,但它已采用了Swyft的平台,该公司广告和平台副总裁理查德o拉百特表示,这类广告非常契合人们使用Tango的方式。一年前,Tango决定不再卖贴纸了,因为向用户要钱总会带来很多摩擦。拉百特称:“在人们沟通过程中放上一道‘留下买路钱’的大门绝不是我们希望带给用户的体验。”所以,就由Swyft来提供这种广告吧。

美国各地许多餐馆和商店星期三向美国退伍军人提供免费服务或优惠,以纪念一年一度的退伍军人节。
按照我们过去三年的观察,感恩节旅游季期间的航班晚点率实际上有所下降——据美国交通运输部的数据显示,去年感恩节航班的晚点率仅为12%,低于2010年的19%。
While newcomer to the list Ariel Foxman, who was appointed managing editor at Time Inc.’s In Style in September 2008, isn’t a regular on a television show as of yet, his fashion director Hal Rubenstein is now a judge onLifetime’s Blush: The Search for the Next Great Make-up Artist. And Foxman’s publication led the way in number of advertising pages, boasting over 1,000 during the first half of 2009.
《请以你的名字呼唤我 》
英国《金融时报》EMBA项目排行榜在对商学院和2011年毕业生进行调查的基础上编制,可以让人们大致了解学员在读EMBA前后的变化。
很多宏伟壮观的博物馆坐落在布鲁日、安特卫普和布鲁塞尔等风景如画的城市中。艺术爱好者可尽情徜徉在中世纪时期的大量艺术瑰宝中。同时,你也不要错过造访宁静小镇、参观哥特式建筑的机会。比利时拥有世界上最好的啤酒、巧克力以及薯条,因此,在那里人人都是美食家。随着第一次世界大战爆发100周年纪念日的临近,未来几年,比利时将成为更多游客的首选。

Discernment to determine whether a particular app, wearable, or sensor can be effective.
Expertise and experience to guide patients on the use of technology.
Partnership with patients in pursuit of optimal health through technology use.
Trials to closely monitor benefits and drawbacks.
Humility to recognize that patients may know and invest much more time than physicians in looking for these tools.34

Conclusions
Based on today’s rapid pace of development and public enthusiasm for the technology marketplace, health apps, wearables, and sensors will soon become integral to our patients’ pursuits of good health and will need to be integrated in clinical practice. Physicians must be active agents in these evolutionary times, guiding patients, advocating for evidence to support the use of technologies, and participating in the development and incorporation of technology in patient wellness journeys. Through clinical stewardship and partnership with patients, physicians can use their expertise and experience to guide the growth of innovations into mainstream health care.

Competing interests
Dr Ho receives no personal financial compensation as the principal investigator of TEC4Home (Telehealth for Emergency-Community Continuity of Care Connectivity via Home Tele-monitoring), a project funded by a Canadian Institutes of Health Research grant. This grant is matched by the Michael Smith Foundation for Health Research and the BC Ministry of Health, with additional support provided by TELUS Health and Sentrian. TELUS Health, Cisco, and Avizia have also provided equipment for display in Dr Ho’s Demonstration and Simulation Studio for Health (DaSSH) at UBC. Mr Yao and Dr Lauscher have no competing interests to declare.


儿童涂料市场受青睐 细分企业抢先机


References

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13. Rhodes RE, Yao CA. Models accounting for intention-behavior discordance in the physical activity domain: A user’s guide, content overview, and review of current evidence. Int J Behav Nutr Phys Act 2015;12:1-14.

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15. Appelboom G, Camacho E, Abraham ME, et al. Smart wearable body sensors for patient self-assessment and monitoring. Arch Public Health 2014;72:28.

16. Chan M, Estève D, Fourniols JY, et al. Smart wearable systems: Current status and future challenges. Artif Intell Med 2012;56:137-156.

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19. Ferdman DJ, Liberman L, Silver ES. A smartphone application to diagnose the mechanism of pediatric supraventricular tachycardia. Pediatr Cardiol 2015;36:1452-1457.

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22. Flodgren G, Rachas A, Farmer A, et al. Interactive telemedicine: Effects on professional practice and health care outcomes. Cochrane Database System Rev 2015;(9):CD002098.

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bent
10.美国密歇根上半岛
n. 锦标赛,冠军,拥护
China’s commercial banks are the control centre of the financial system and supply almost 70% of the financing that feeds the real economy.
“我们为最佳影片奖颁奖通告期间出现的失误,向《月光男孩》、《爱乐之城》、沃伦?比蒂、费?唐纳薇、以及奥斯卡奖观众表示诚挚地道歉。颁奖嘉宾收到的是错误奖项的信封,这个失误一经发现立刻得到了纠正。”
n. 示范,实证,表达,集会
8. Sturgill Simpson “Metamodern Sounds in Country Music” (High Top Mountain) A throwback progressive hunkered down with a whip-smart band: country music has seen this before. But on his breakthrough second album, Sturgill Simpson made it a pliable trademark, grounded at every turn by his winning, seen-it-all baritone.
The report ranks brands based on financial performance, its influence on customers, and its power to command a premium price or drive company sales.
Weaker demand from emerging markets made 2015 the worst year for world trade since the aftermath of the global financial crisis, highlighting rising fears about the health of the global economy.
Online peer-to-peer broker Ezubao previously cheated about 900,000 investors out of more than 50 billion RMB through a giant Ponzi scheme, the Xinhua News Agency reported in February.

Kendall Ho, MD, FRCPC, Christopher Yao, MSc, Helen Novak Lauscher, PhD. Part 2: Health apps, wearables, and sensors: The advancing frontier of digital health. BCMJ, Vol. 59, No. 10, December, 2017, Page(s) 503-506 - Clinical Articles.



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Halpern SD, Ubel PA, Caplan AL, Marion DW, Palmer AM, Schiding JK, et al. Solid-organ transplantation in HIV-infected patients. N Engl J Med. 2002;347:284-7.

About the ICMJE and citation styles

The ICMJE is small group of editors of general medical journals who first met informally in Vancouver, British Columbia, in 1978 to establish guidelines for the format of manuscripts submitted to their journals. The group became known as the Vancouver Group. Its requirements for manuscripts, including formats for bibliographic references developed by the U.S. National Library of Medicine (NLM), were first published in 1979. The Vancouver Group expanded and evolved into the International Committee of Medical Journal Editors (ICMJE), which meets annually. The ICMJE created the This marks the first time that Google has topped the list since 2011. to help authors and editors create and distribute accurate, clear, easily accessible reports of biomedical studies.

5. Starbucks. Brand love: 26% / Social Business Index Rank: 26
One of the highest-paid Bollywood actresses, Deepika Padukone hold the third position in the list of 10 most beautiful women of 2015. She is considered a sex symbol and style icon in India. Padukone ranks high on various listings of the most attractive Indian women. She is cited by her figure, height, smile, and eyes as her distinctive physical features. She is an active celebrity endorser for several brands and products, including Tissot, Sony Cyber-shot, Nescafe, Vogue eyewear, Maybelline and Pepsi, among others.
根据世界黄金协会(World Gold Council)的数据,自2008年以来全球黄金供应每年都增长,这一增长在去年陷入停滞。作为世界最大的黄金生产国,去年中国的黄金供应创纪录地下降9%,这是自1980年来中国的黄金产出第二次下降。
5.电子烟

桑尼伯恩和他的父母以及11岁的妹妹朱莉娅住在佛蒙特州的布里斯托尔,他正在寻求民主党的提名。

  • Only the first three authors are listed, followed by "et al."
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“It is exceptionally unlikely that we would be witnessing a record year of warmth, during a record-warm decade, during a several decades-long period of warmth that appears to be unrivaled for more than a thousand years, were it not for the rising levels of planet-warming gases produced by the burning of fossil fuels,” Michael E. Mann, a climate scientist at the Pennsylvania State University, said in an email.
In the Robot World Cup Soccer final on June 30th the Dutch robots weren’t up against the Chinese team “Water” from Beijing. Within a minute the Chinese team scored a goal. The Dutch made an equalizer before half-time, yet in the second half team Water scored again.

BCMJ Guidelines for Authors

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